< >


Product name Granzyme B Antibody
Catalog no 4ab071529
Size 100 μl


Description 4ab071529|Granzyme B Antibody
Reactivity Human, Mouse, Rat
Immunogen Synthesized peptide derived from human Granzyme B.
Host Rabbit
Clonality Polyclonal
Application WB, IHC
Conjugate Unconjugated
Synonyms; CCPI; CGL-1; CGL1; CSP-B
Storage Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Background This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

image of Granzyme B Antibody


Granzyme B Antibody