Overview
| Product name | TBK1 Antibody (S172) |
| Catalog no | 4ab032308 |
| Size | 100 μl |
Applications
| Background | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. |
| Storage | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugate | Unconjugated |
| Application | IHC-P, WB |
| Clonality | Polyclonal |
| IsoType | Rabbit Ig |
| Host | Rabbit |
| Immunogen | This TBK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 amino acids from human TBK. |
| Reactivity | Human, Mouse |
| Description | 4ab032308|TBK1 Antibody (S172) |
image of TBK1 Antibody (S172)
¥2480.00
TBK1 Antibody (S172)
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