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Overview

Product name Bi-Phospho-Syk(Y525/526) Antibody
Catalog no 4ab031350
Size 100 μl

Applications

Background Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.
Storage Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylate
Conjugate Unconjugated
Application WB, IHC-P
Clonality Polyclonal
IsoType Rabbit Ig
Host Rabbit
Immunogen This Syk Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y525/526 of human Syk.
Reactivity Human
Description 4ab031350|Bi-Phospho-Syk(Y525/526) Antibody

image of Bi-Phospho-Syk(Y525/526) Antibody

¥800.00

Bi-Phospho-Syk(Y525/526) Antibody

规格:

货期:现货