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Overview

Product name Dnmt3b Antibody
Catalog no 4ab030108
Size 100 μl

Applications

Description 4ab030108|Dnmt3b Antibody
Reactivity Human
Immunogen This Dnmt3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-417 amino acids from human Dnmt3b.
Host Rabbit
IsoType Rabbit Ig
Clonality Polyclonal
Application WB, IHC-P
Conjugate Unconjugated
Storage Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome.

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¥1200.00

Dnmt3b Antibody

规格:

货期:现货